Jesus, who is God, is the only Mediator. To have any others is blasphemy.

Chapter 8: Of Christ the Mediator (Parts Three & Four)

It pleased God from all eternity past to ordain Jesus, the eternally Begotten Son of God, to be the only Mediator between God and man (1 Timothy 2:5).  As Mediator, Jesus is Prophet, Priest, and King. 

As the Prophet, He represents God to man, not only declaring God’s Word (Mark 1:14, 38), but by being the Incarnate Word of God (John 1:1). 

As our Great High Priest, He represents man to God, not only offering a sacrifice for man’s sin, but offering Himself as the once-for-all, never-to-be-repeated Sacrifice for man’s sin (Hebrews 7:27, 10:11-12).  He continues as our Great High Priest, ever living to make intercession for us (Hebrews 7:25). 

As our King, He rules over all things (Ephesians 1:22, Revelation 19:16).

Christ is the Head of His Body, the Church (Colossians 1:18).  He is the Savior of His Church (Ephesians 5:23).  He is the Heir of all things (Hebrews 1:2).  He is the Judge of all the world (John 5:22; 2 Corinthians 5:10).

(Part Four)

The Son of God is the second Person in the Holy Trinity.  He is eternal God, equal in every way with the Father and the Holy Spirit—including in His substance, essence, and being.  He is the physical expression of the brightness of the Father's glory (Hebrews 1:3).  Everything that is made was made through Christ (John 1:3; Colossians 1:16).  He also sustains and governs all He has created (Colossians 1:16).

In the fullness of time, Christ assumed a human nature (Philippians  2:7), was conceived by a supernatural act of the Holy Spirit (Luke 1:35; Matthew 1:20) and born of the virgin, Mary (Matthew 1:23; Luke 2:4-7).  While never being any less God, He became a man in every way except that He was without sin (Hebrews 4:15). 

From that time forward and on into eternity, Christ has two natures, divine and human, that are inseparably joined in one Person.  His two natures are distinct, yet never separated, never confused, or co-mingled as one nature.  This God Man is the one and only Mediator between God and man (1 Timothy 2:5).